How To Use Letrozole

How To Use Letrozole in Your Steroid Cycle

Do you want to know how much letrozole to take on a steroid cycle? We are going to cover this topic in depth.  There are many factors that determine the dosage of an aromatase inhibitor (AI), but there is general consensus on what does and does not work for all people with low testosterone levels. The most common question about these drugs is how much should I take on a steroid cycle? Let’s answer that first before we go any further!

What is Letrozole?

Letrozole is a selective aromatase inhibitor that means it inhibits the conversion of testosterone to estrogen. In bodybuilding, this drug is commonly used in conjunction with highly estrogenic anabolic steroids to reduce or prevent estrogenic side effects resulting from elevated testosterone levels which causes high estrogen levels.

There are three common types of steroidal compounds that produce excess estrogen through aromatization: testosterones, 19-nortestosterone (or nandrolone) and 17 alpha alkylated steroids. And for these four main categories there are mainly two uses for Letrozole in bodybuilding cycles:

  1.   Preventing gynecomastia – blocking the conversion of Testosterone into estradiol (estrogen) by inhibiting the aromatase enzyme.
  2.   Post cycle therapy – maintaining lower levels of estrogen after a cycle of steroids to avoid a rebound and the onset of gynecomastia.

How does it work on a steroid cycle?

Letrozole works to reduce or prevent estrogenic side effects by inhibiting the aromatase enzyme, which is responsible for converting testosterone to estrogen. By blocking this conversion, less estrogen is produced in the body. This can be massively beneficial during steroid cycles, as there are many negative side effects associated with high estrogen levels (water retention/high blood pressure/bloating/gyno).

How much Letrozole should you take on a steroid cycle?

The amount of letrozole that you should take on a steroid cycle will vary depending on the type of steroidal compounds you are taking. If you are taking testosterone, then the general consensus is that you should take 2.5mg every 4th day to prevent high estrogen levels. If you are taking Nandrolone (a progestin based steroid), then you should take 1.75 mg every 4th day. But you will also need to take Cabergoline (Caberlin) as this will keep the levels of progesterone down also which Nandrolone can promote while on cycle.

Remember that these dosages are just general guidelines, and you may need an individual dosage depending on your individual situation. For instance, if you are taking very large amounts of steroids then it may be necessary to take more than the recommended dosage. If you have estrogenic based gynecomastia already, taking 2.5mg per day for one week should help to stop and reverse this issue.

Is Letrozole banned? 

It is not considered a controlled substance by the FDA, and it does not appear on any lists of prohibited drugs. However, because letrozole has profound effects on natural testosterone production for men, many athletic organizations discourage its use. The World Anti-Doping Agency (WADA) has included it on their “Prohibited Substances” list which limits application in professional sports.

Be advised that there are various laws regarding purchasing supplements containing ingredients such as Letrozole (or aromatizable steroids). For example, in Australia, even possession or purchase of bodybuilding substances such as letrozole is punishable by law if bought within the country.

Benefits of Taking Letrozole

There are many benefits to taking Letrozole on a steroid cycle such as:

  • Reducing estrogenic side effects of steroids such as water retention and estrogenic side effects.
  • Increasing fat loss – By blocking the production of estrogen, this drug can help you burn more calories and thereby increase your ability to lose weight and gain muscle mass even when using aromatizable steroids (which normally hinder fat burning). However, letrozole alone will not be enough to maximize your calorie expenditure; diet and exercise also need to be included for maximum results.
  • Decreased risk of cardiovascular disease – studies have shown that estrogen contributes to heart problems. Therefore, using aromatase inhibitors may be good for your cardiovascular health.

Side Effects

Just like any other drug, if Letrozole is abused, it has the potential to cause side effects. Some of the more common side effects include:

  • Hot flashes
  • Headaches
  • Dizziness
  • Fatigue
  • Nausea
  • Vomiting

These side effects are usually mild and will subside once you stop taking the drug. However, in some cases there can be more severe side effects such as liver damage, blood clots and increased risk of heart attack or stroke. If you experience any of these severe side effects, you should stop taking Letrozole and seek medical help.

What other medications should I avoid when taking Letrozole?

Letrozole is often stacked with other drugs to maximize its benefits. However, you should always ask your doctor or experienced provider before taking Letrozole with any medications because they could decrease the effectiveness of Letrozole or interfere with each other causing serious side effects.

Some examples of some common drug combinations include:

  • Letrozole and Anastrozole – This combination has been popular for years due to its ability to prevent estrogen production while maximizing fat loss without reducing muscle mass. But this is for people with severely high levels of estrogen who need to lower this level quickly.
  • Nolvadex (Tamoxifen) and letrozole – This stack will not only reduce estrogen but also block testosterone receptors on cells preventing further hormone activity in these cells. Such a combo can be great for increasing lean muscle mass. But again, this is for people who are prone to estrogenic side effects, not the average user.
  • Letrozole and HCG – This stack is often used by bodybuilders who are looking to preserve their muscle mass while on a calorie restricted diet. The HCG helps to prevent muscle loss and keep the testes alive and functioning while the Letrozole blocks the effects of high estrogen levels.

As you can see, there are many different ways that you can use Letrozole in your steroid cycle. It is important to tailor the dosage and drug combinations to fit your own individual needs. By doing so, you can maximize the benefits of this powerful aromatase inhibitor. It is also worth noting that this should only be used as a preventative drug or used once estrogenic issues occur, as having too low levels of estrogen will hinder muscle growth.

What are some alternatives to Letrozole?

If you are looking for a drug that can block the effects of estrogen, there are several alternatives to Letrozole. Some of the more popular ones include:

  • Aromasin (exemestane) – This drug is structurally similar to letrozole and is also an aromatase inhibitor. It is often used as a treatment for breast cancer in post-menopausal women. This is used in extreme cases as it is a type one AI and will lower the estrogen levels to nearly zero, which can be bad for muscle gain and bodily functioning. The most effective version of this substance is Aromex from Alpha Pharma Healthcare.
  • Arimidex (Anastrozole) – Another popular aromatase inhibitor that is structurally similar to Letrozole. This is the most popular, as running this drug at 0.5 mg every other day from week 4 of your cycle can stop your estrogen levels from climbing to high and causing issues. The most effective version of this substance is the Arimidex from Dragon Pharma.
  • Femara (Letrozole) – This is the original letrozole drug that was developed by Novartis. It is currently approved by the FDA for the treatment of breast cancer in post-menopausal women. The most effective version of this substance is FEMARA 2.5mg from Dragon Pharma.

Final Thoughts:

Letrozole is an aromatase inhibitor that was originally used by bodybuilders and athletes to prevent the effects of estrogen in various steroid cycles. It can be a great addition to your steroid cycle because it can help increase fat loss without reducing gains in muscle mass. Just remember that the effects of this drug are not permanent, and you will need to take some time off from Letrozole in between steroid cycles.

There are many different ways that you can use Letrozole in your steroid cycle. It is important to tailor the dosage and drug combinations to fit your own individual needs. By doing so, you can maximize the benefits of this powerful aromatase inhibitor!

Luckily, within Our US Pharmaceutical Store, you can find all types or AI and SERMs including original Injectable Steroids, Oral Steroids, PCT Care, Sexual Health Aids and more to build the best, safest and most effective cycle for you, your body and your desired goals!

We have an expert team at hand who can help you build the perfect cycle with the correct preventative substances needed such as Letrozole in order for you to have the most effective cycle and performance possible. All of our inventory is original and straight from the main medical manufacturers which can also be verified using their own websites.

We offer easy payment options such as US Bank Transfer, PayPal, Credit Cards, and Major Cryptocurrencies with discreet and guaranteed delivery to the United States! So our valued clients can start to build their perfect cycles for their desired goals with confidence!  

Let us know how the use of Letrozole goes for you by leaving a comment below!

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